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Peter Greenwald (auth.), Vincenzo Zappia, Fulvio Della's Advances in Nutrition and Cancer 2 PDF

By Peter Greenwald (auth.), Vincenzo Zappia, Fulvio Della Ragione, Alfonso Barbarisi, Gian Luigi Russo, Rossano Dello Iacovo (eds.)

ISBN-10: 144193331X

ISBN-13: 9781441933317

ISBN-10: 1475732309

ISBN-13: 9781475732306

This quantity comprises contributions provided on the moment foreign Sym­ posium on foodstuff and melanoma, held in Naples, Italy, in October 1998 on the nationwide Tumor Institute "Fondazione Pascale." throughout the convention, specialists from diversified disciplines mentioned pivotal and well timed matters at the interactions among human meals and the improvement of malignancies. evaluating the topics of this assembly with these mentioned on the First Sympo­ sium in 1992, the main medical developments definitely derive from the huge use of molecular methods to accomplish learn in meals. in addition, the basic remark of R. Doll and R. Peto (1981), which prompt that at the very least 35% of all cancers (with huge changes between diversified tumors) should be avoided via nutritional regimens, has been definitively proven by means of epidemiological experiences. however, the relationships among nutrition and melanoma are rather tricky and intricate; it really is tough, and while now not methodologically right, to lessen them to basic phrases. Metabolic and hormonal elements, contaminants and organic brokers, and deficiency of particular protecting foodstuff are all items of a similar puzzle.

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31. R, and Miller AB. A case-control study of diet and colo-rectal cancer. Int J Cancer. 1980;26:757-768. 32. Potter ID. and McMichael Al Diet and cancer of the colon and rectum: a case-control study. J Nat! Cancer Inst. 1986;76:557-569. Nutritional Factors in Human Cancers 39 33. , and Stanish W. Energy intake: its relationship to colon cancer risk. J Nat! Cancer Inst. 1987;78:853-861. 34. , and West D. Dietary epidemiology of cancer of the colon in western New York. Am J Epidemiol. 1988;128:490-503.

The transfer of the methyl group from 5-methyl tetrahydrofolate to homocysteine forms methionine, a reaction also requiring cobalamin. If compensatory production of methionine is hindered by insufficient 5-methyl tetrahydrofolate level, and possibly cobalmine levels, the methyl supply for DNA methylation may be inadequate. Because these processes would appear to be important for cell types in general, it is possible that folate deficiency could be a risk factor for numerous cancer types. In fact, some supportive though inconclusive evidence exists for various cancer sites.

1983;32:1-5. 41. , Gentile A, and Franceschi S. A casecontrol study of diet and colo-rectal cancer in northern Italy. Int J Cancer. 1988;41:492-498. 42. , and Harrison L. Food items and food groups as risk factors in a case-control study of diet and colo-rectal cancer. Int J Cancer. 1983;32:155-161. 43. B. A Case-control study of proximal and distal colon cancer and diet in Wisconsin. Int J Cancer. 1988;42:167-175. 44. , and Kaldor I A populationbased case-control study of colorectal cancer in Majorca.

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Advances in Nutrition and Cancer 2 by Peter Greenwald (auth.), Vincenzo Zappia, Fulvio Della Ragione, Alfonso Barbarisi, Gian Luigi Russo, Rossano Dello Iacovo (eds.)


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